Ka-hortagga Insulin-ka (INS) Qalabka ELISA ee Ka-hortagga Jirka

Sharaxaad Gaaban:

Xirmadan waxa loo isticmaalaa in lagu ogaado tayaysan in vitro ee unugyada difaaca insulin-ka ee serum bini aadamka.

Dadka caadiga ah, joogitaanka unugyada difaaca jirka ee insulinta ayaa ka dhigaysa inay u nugul yihiin inay qaadaan Nooca 1aad ee Sonkorowga Mellitus (T1DM). Ka-hortagga-insulin-ka-hortagga waxaa laga yaabaa in la soo saaro sababtoo ah dhaawaca β-unugga, markaa ogaanshadoodu waxay u adeegi kartaa calaamad muujinaysa dhaawaca β-unugga ee difaaca jirka. Waxay sidoo kale yihiin calaamadaha difaaca ee ugu horreeya ee ka soo baxa carruurta khatarta sare leh ee T1DM, waxaana loo isticmaali karaa ogaanshaha hore iyo ka hortagga T1DM, iyo sidoo kale bixinta tilmaamo gaar ah oo ku saabsan ogaanshaha iyo saadaalinta T1DM.

Joogitaanka unugyada difaaca insulin ee dhiigga ayaa ah sabab muhiim ah oo iska caabbinta insulinta. Bukaanka macaanka qaba ee qaata daawaynta insuliinka waxa laga yaabaa inay yeeshaan caabbinta insulinta sababta oo ah soo saarista unugyada difaaca insulin, oo lagu garto kordhinta qiyaasta insulinta laakiin xakamaynta gulukoosta dhiigga ee aan ku qanacsanayn. Waqtigan xaadirka ah, unugyada difaaca insulin waa in la tijaabiyaa; Natiijooyinka togan ama titers kordhay waxay u adeegi karaan caddayn ujeedo ah caabbinta insulin. Intaa waxaa dheer, ogaanshahani wuxuu ka ciyaaraa door caawiye ah ogaanshaha cudurka Insulin Autoimmune Syndrome (IAS).